A high-throughput web-server capable of predicting the functional consequences of both coding variants, i.e. non-synonymous single nucleotide variants (nsSNVs), and non-coding variants in the human genome.
|Use this option to return predictions capable of discriminating between disease-causing mutations and neutral polymorphisms.
|Use this option to return predictions capable of distinguishing between cancer-promoting/driver mutations and other germline polymorphisms
|Use this option to return a list of ranked variants that are potentially functionally relevant to to your disease of interest.
|Our MKL algorithm integrates functional annotations from ENCODE with nucleotide-based HMMs. Use this option to return predictions on both coding and non-coding variants.
|Our XF algorithm incorporates extra features
|CScape predicts the oncogenic status (disease-driver or neutral) of somatic point mutations